| slovo | definícia |
mechanism of action
(gcide) | mechanism of action \mech"an*ism of ac"tion\, n. (Medicine,
Biochemistry)
The mechanism[2] by which a pharmacologically active
substance produces an effect on a living organism or in a
biochemical system; as, the mechanism of action of
actinomycin involves its binding to DNA. The mechanism of
action is usually considered to include an identification of
the specific molecular targets to which a pharmacologically
active substance binds or whose biochemical action it
influences; a general recognition of the broad biochemical
pathways (such as DNA synthesis, protein synthesis,
cholesterol synthesis) which are inhibited or affected by a
substance is termed its mode of action.
[PJC] |
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