slovodefinícia
penicillinase
(encz)
penicillinase, n:
Penicillinase
(gcide)
Penicillinase \Pen`i*cil"lin*ase\, n. (Bioch.)
An enzyme which destroys the antibacterial activity of
penicillin by hydrolyzing the amide bond in the beta-lactam
ring. Many penicillinases are known, and are produced by a
wide variety of bacteria. The production of penicillinase is
one of the mechanisms by which bacteria may become resistant
to penicillins. Penicillinase production in various bacterial
species may be induced, i.e., it may occur only when
stimulated by the presence of penicillin in the culture
medium, or it may be constitutive, i.e., it may occur
whenever the cells are producing protein. Molecular weights
of the various penicillinases tend to cluster near 50,000.
[PJC]
penicillinase
(wn)
penicillinase
n 1: enzyme produced by certain bacteria that inactivates
penicillin and results in resistance to that antibiotic
[syn: penicillinase, beta-lactamase]
podobné slovodefinícia
penicillinase-resistant antibiotic
(encz)
penicillinase-resistant antibiotic, n:
Penicillinase
(gcide)
Penicillinase \Pen`i*cil"lin*ase\, n. (Bioch.)
An enzyme which destroys the antibacterial activity of
penicillin by hydrolyzing the amide bond in the beta-lactam
ring. Many penicillinases are known, and are produced by a
wide variety of bacteria. The production of penicillinase is
one of the mechanisms by which bacteria may become resistant
to penicillins. Penicillinase production in various bacterial
species may be induced, i.e., it may occur only when
stimulated by the presence of penicillin in the culture
medium, or it may be constitutive, i.e., it may occur
whenever the cells are producing protein. Molecular weights
of the various penicillinases tend to cluster near 50,000.
[PJC]
penicillinase-resistant antibiotic
(wn)
penicillinase-resistant antibiotic
n 1: a form of penicillin that is not rendered inactive by
penicillinase

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